Crews responded to the fire on the 1500 block of North Viewsite Drive in Hollywood Hills at approximately 11:20 p.m. at a recently built three-story, 6,000-square-foot home.
Firefighters were working to gain access to the flames in the ceiling when it fell on them.
An unidentified firefighter was critically injured and transported to a local hospital in grave condition.
The Associated Press has reported that the firefighter was trapped in the blaze had no pulse or heartbeat when he was removed, but that they were restored.
"The fire was in the ceiling area, between the ceiling and the roof and the attic space and behind a wall near a fireplace," LAFD Deputy Chief Mario Rueda told KABC-TV.
Two people were inside the home when the fire started but were able to get out safely.
Four of the injured firefighters are from the city of Los Angeles while the other two are from Los Angeles County.
The cause of the fire remained under investigation.
Firehouse.com will provide more information on this story as it becomes available.
