The names of the three have not been released.
Alaska State Troopers in Glennallen received the call of the fire at 6:40 a.m. Saturday and responded to the single-family, two-story home at Mile 102 Richardson Highway. The home was destroyed.
Investigators found the remains of the three people in the home's ashes.
Two deputy state fire marshals investigated the fire Saturday, said trooper spokesman Greg Wilkinson.
The fire may have started near a wood-fired furnace, Wilkinson said.
Copper Center is a community of about 450 people on the Richardson Highway between Miles 101 and 105. It is on the west bank of the Copper River at the confluence of the Klutina River.
Six people in Alaska have been killed by fire this year, Wilkinson said.
