Five, Including Three Kids, Killed in Albany, NY, House Fire

Albany firefighters encountered heavy fire showing and learned two of the five victims were trapped.

Oct. 6, 2025

2 min read

Steve Hughes

Times Union, Albany, N.Y.

(TNS)

Oct. 6—ALBANY — A fire on Twiller Street on Monday morning left five people dead.

When fire crews arrived at the two-story home at 23 Twiller St., just before 10:45 a.m., they found the house engulfed in flames, with fire shooting out the first-floor window. More than 40 firefighters responded to the scene.

Two children and an adult were transported to Albany Medical Center Hospital and died at the hospital. Two other people, an adult and a child, were trapped inside the home and pronounced dead at the scene, Police Chief Brendan Cox said at a news conference.

Cox said the department would not be releasing the victims' names and ages until family had been notified and cautioned the investigation was still in its early stages.

"It's a very sad and tragic day here," Cox told reporters, according to a video posted on Spectrum News.

Fire Chief Joseph Gregory said the fire also damaged neighboring homes at 21 and 25 Twiller St.

The cause of the blaze remains under investigation, police said.

Neighbors, some of whom have lived on Twiller Street for decades, described the residents at 23 Twiller St. as good neighbors who largely kept to themselves. Two teenage boys who live at the house were known for offering their services in mowing lawns in summer and shoveling driveways in winter.

Patty Prusinski, who has lived on Twiller Street for 60 years, said the teens shoveled her driveway in the past. It was not clear if the boys were among the victims.

Neighbors described an environment where neighbors minded their own business but also looked out for each other in more trying times.

"This is a great street," Prusinski said. "It's a wonderful neighborhood."

Charles Taylor, who lives across the street, said several generations lived in the home and that one resident used a wheelchair.

He said he saw the residents of the house every day.

Mike Goodwin contributed reporting to this article.